Engineering global regulator Hha of Escherichia coli to control biofilm dispersal
نویسندگان
چکیده
منابع مشابه
Engineering global regulator Hha of Escherichia coli to control biofilm dispersal
The global transcriptional regulator Hha of Escherichia coli controls biofilm formation and virulence. Previously, we showed that Hha decreases initial biofilm formation; here, we engineered Hha for two goals: to increase biofilm dispersal and to reduce biofilm formation. Using random mutagenesis, Hha variant Hha13D6 (D22V, L40R, V42I and D48A) was obtained that causes nearly complete biofilm d...
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ژورنال
عنوان ژورنال: Microbial Biotechnology
سال: 2010
ISSN: 1751-7915
DOI: 10.1111/j.1751-7915.2010.00220.x